• Postbus 513, Helix Building

    5600 MB Eindhoven

    Netherlands

  • De Groene Loper 3, Helix Building (STO 3.39)

    5612 AE Eindhoven

    Netherlands

Research Output

2018

Effect of formulation and processing parameters on the size of mPEG-b-p(HPMA-Bz) polymeric micelles

Bagheri, M., Bresseleers, J., Varela-Moreira, A., Sandre, O., Meeuwissen, S. A., Schiffelers, R. M., Metselaar, J. M., Van Nostrum, C. F., van Hest, J. C. M. & Hennink, W. E., 18 Dec 2018, In : Langmuir. 34, 50, p. 15495-15506 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
1 Downloads (Pure)

Engineering protein-based nanoparticle conjugates for nanomedicine applications

van Hest, J., Pille, J., Abdelghani, M., Timmermans, S., Vervoort, D. & Pretto, C., 19 Aug 2018, 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond .

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Erythrocyte membrane modified janus polymeric motors for thrombus therapy

Shao, J., Abdelghani, M., Shen, G., Cao, S., Williams, D. S. & van Hest, J. C. M., 22 May 2018, In : ACS Nano. 12, 5, p. 4877-4885 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Citations (Scopus)
64 Downloads (Pure)

Feedback-induced temporal control of “breathing” polymersomes to create self-adaptive nanoreactors

Che, H., Cao, S. & van Hest, J. C. M., 25 Apr 2018, In : Journal of the American Chemical Society. 140, 16, p. 5356–5359 4 p., 16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
42 Citations (Scopus)
113 Downloads (Pure)

Metal ion-induced self-assembly and packaging of CCMV nanocapsules

Schoonen, L., van Eldijk, M. B. & van Hest, J. C. M., 5 Jun 2018, Protein scaffolds: design, synthesis, and applications. Udit, A. K. (ed.). Dordrecht: Springer, p. 57-67 11 p. (Methods in Molecular Biology; vol. 1798).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Modification of CCMV nanocages for enzyme encapsulation

Schoonen, L. & van Hest, J. C. M., 5 Jun 2018, Protein Scaffolds : Design, Synthesis, and Applications. Udit, A. K. (ed.). Dordrecht: Springer, p. 69-83 15 p. (Methods in Molecular Biology; vol. 1798).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Modular, bioorthogonal strategy for the controlled loading of cargo into a protein nanocage

Schoonen, L., Eising, S., van Eldijk, M. B., Bresseleers, J., Van Der Pijl, M., Nolte, R. J. M., Bonger, K. M. & van Hest, J. C. M., 18 Apr 2018, In : Bioconjugate Chemistry. 29, 4, p. 1186-1193 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
77 Downloads (Pure)

Nanoreactors for green catalysis

De Martino, M. T., Abdelmohsen, L. K. E. A., Rutjes, F. P. J. T., van Hest, J. C. M. & Hessel, V. (Guest ed.), 29 Mar 2018, In : Beilstein Journal of Organic Chemistry. 14, p. 716–733 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
19 Citations (Scopus)
108 Downloads (Pure)

PH-induced transformation of biodegradable multilamellar nanovectors for enhanced tumor penetration

Cao, S., Abdelmohsen, L. K. E. A., Shao, J., van den Dikkenberg, J., Mastrobattista, E., Williams, D. S. & van Hest, J. C. M., 20 Nov 2018, In : ACS Macro Letters. 7, 11, p. 1394-1399 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Citations (Scopus)
48 Downloads (Pure)

Polymers at the interface with biology

Deming, T. J., Klok, H. A., Armes, S. P., Becker, M. L., Champion, J. A., Chen, E. Y. X., Heilshorn, S. C., van Hest, J. C. M., Irvine, D. J., Johnson, J. A., Kiessling, L. L., Maynard, H. D., De La Cruz, M. O., Sullivan, M. O., Tirrell, M. V., Anseth, K. S., Lecommandoux, S., Percec, S., Zhong, Z. & Albertsson, A. C., 13 Aug 2018, In : Biomacromolecules. 19, 8, p. 3151-3162 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
3 Citations (Scopus)
1 Downloads (Pure)

Residue-specific incorporation of noncanonical amino acids for protein engineering

van Eldijk, M. B. & van Hest, J. C. M., 2018, Noncanonical amino acids: methods and protocols. Lemke, E. A. (ed.). New York: Humana Press, p. 137-145 9 p. (Methods in Molecular Biology; vol. 1728).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Self-assembled nanoreactors based on peptides and proteins

Timmermans, S. B. P. E. & van Hest, J. C. M., 1 May 2018, In : Current Opinion in Colloid and Interface Science. 35, p. 26-35 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
14 Citations (Scopus)
89 Downloads (Pure)

Self-assembly and stabilization of hybrid cowpea chlorotic mottle virus particles under nearly physiological conditions

Timmermans, S. B. P. E., Vervoort, D. F. M., Schoonen, L., Nolte, R. J. M. & van Hest, J. C. M., 16 Nov 2018, In : Chemistry - An Asian Journal. 13, 22, p. 3518-3525 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
23 Downloads (Pure)

Sialic acid blockade suppresses tumor growth by enhancing t-cell–mediated tumor immunity

Bull, C., Boltje, T. J., Balneger, N., Weischer, S. M., Wassink, M., van Gemst, J. J., Bloemendal, V., Boon, L., van der Vlag, J., Heise, T., den Bronk, M. & Adema, G. J., 1 Jul 2018, In : Cancer Research. 78, 13, p. 3574-3588 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
29 Citations (Scopus)

Temperature-induced collapse of elastin-like peptides studied by 2DIR spectroscopy

Selig, O., da Cunha, A. M. D. C. V., van Eldijk, M. B., van Hest, J. C. M., Jansen, T. L. C., Bakker, H. J. & Rezus, Y. L. A., 30 Aug 2018, In : Journal of Physical Chemistry B. 122, 34, p. 8243-8254 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
43 Downloads (Pure)

The hallmarks of living systems: Towards creating artificial cells

Amy Yewdall, N., Mason, A. F. & Van Hest, J. C. M., 6 Oct 2018, In : Interface Focus. 8, 5, 15 p., 20180023.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
12 Citations (Scopus)
72 Downloads (Pure)

Using pulse electric fields to improve permeabilization of DODAB vesicles

Rossi Batista, I., 23 Oct 2018, Eindhoven: Technische Universiteit Eindhoven. 53 p.

Research output: ThesisPd Eng Thesis

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: Approaches towards capsid rupture and gel repair

Schoenmakers, D. C., Schoonen, L., Rutten, M. G. T. A., Nolte, R. J. M., Rowan, A. E., van Hest, J. C. M. & Kouwer, P. H. J., 28 Feb 2018, In : Soft Matter. 14, 8, p. 1442-1448 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
113 Downloads (Pure)
2017

A dibenzoazacyclooctyne as a reactive chain stopper for [2]rotaxanes

Hou, Z-Y., Yeniad, B., van Guyse, J., Woisel, P., Mullen, K. M., Rutjes, F. P. J. T., van Hest, J. C. M. & Hoogenboom, R., 8 Jun 2017, In : European Journal of Organic Chemistry. 2017, 21, p. 3107-3113 7 p., 21.

Research output: Contribution to journalArticleAcademicpeer-review

Alternative application of an affinity purification tag: hexahistidines in ester hydrolysis

Schoonen, L., van Esterik, K. S., Zhang, C., Ulijn, R. V., Nolte, R. J. M. & van Hest, J. C. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 14772.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
85 Downloads (Pure)

Artificial cells: synthetic compartments with life-like functionality and adaptivity

van Hest, J. C. M. & Buddingh, B. C., 17 Jan 2017, In : Accounts of Chemical Research. 50, 4, p. 769–777 9 p., 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
146 Citations (Scopus)
140 Downloads (Pure)

Bio-inks for 3D bioprinting: recent advances and future prospects

Donderwinkel, I., van Hest, J. C. M. & Cameron, N. R., 20 Aug 2017, In : Polymer Chemistry. 8, 31, p. 4451-4471 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

68 Citations (Scopus)

Coiled-coil mediated activation of oligo-arginine cell-penetrating peptides

Bode, S. A., Kruis, I. C., Adams, P. J. H. M., Boelens, W. C., Pruijn, G., van Hest, J. C. M. & Löwik, D. W. P. M., 17 Jan 2017, In : ChemBioChem. 18, 2, p. 185–188 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
113 Downloads (Pure)

Continuous fabrication of polymeric vesicles and nanotubes with fluidic channels

Peng, F., Deng, N-N., Tu, Y., van Hest, J. C. M. & Wilson, D. A., 21 Apr 2017, In : Nanoscale. 9, 15, p. 4875-4880 6 p., 15.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Controlling the morphology of copolymeric vectors for next generation nanomedicine

Williams, D. S., Pijpers, I. A. B., Ridolfo, R. & van Hest, J. C. M., 10 Aug 2017, In : Journal of Controlled Release. 259, 10 august 2016, p. 29-39 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Citations (Scopus)
112 Downloads (Pure)

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 21 Feb 2017, In : ACS Macro Letters. 6, 2, p. 144 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
2 Citations (Scopus)

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 14 Feb 2017, In : Macromolecules. 50, 3, p. 713 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 13 Feb 2017, In : Biomacromolecules. 18, 2, p. 315 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 282 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
1 Citation (Scopus)

Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 8 Feb 2017, In : Chemical Reviews. 117, 3, p. 900 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Evaluation of dextran(ethylene glycol) hydrogel films for giant unilamellar lipid vesicle production and their application for the encapsulation of polymersomes

Mora, N. L., Gao, Y., Gutierrez, M. G., Peruzzi, J., Bakker, I., Peters, R. J. R. W., Siewert, B., Bonnet, S., Kieltyka, R. E., van Hest, J. C. M., Malmstadt, N. & Kros, A., 4 Sep 2017, In : Soft Matter. 13, 33, p. 5580-5588 9 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
85 Downloads (Pure)

Expansion of the assembly of cowpea chlorotic mottle virus towards non-native and physiological conditions

Schoonen, L., Maas, R. J. M., Nolte, R. J. M. & van Hest, J. C. M., 17 Aug 2017, In : Tetrahedron. 73, 33, p. 4968-4971 4 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
86 Downloads (Pure)

Hierarchical self-assembly of a copolymer-stabilized coacervate protocell

Mason, A. F., Buddingh, B. C., Williams, D. S. & van Hest, J. C. M., 6 Dec 2017, In : Journal of the American Chemical Society. 139, 48, p. 17309-17312 4 p., 48.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
30 Citations (Scopus)
117 Downloads (Pure)

Legomedicine - a versatile chemo-enzymatic approach for the preparation of targeted dual-labeled llama antibody-nanoparticle conjugates

van Lith, S. A. M., van Duijnhoven, S. M. J., Navis, A. C., Leenders, W. P. J., Dolk, E., Wennink, J. W. H., Nostrum, van, C. F. & van Hest, J. C. M., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 539-548 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
20 Citations (Scopus)
83 Downloads (Pure)

Morphology under control: engineering biodegradable stomatocytes

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Williams, D. S. & van Hest, J. C. M., 21 Nov 2017, In : ACS Macro Letters. 6, 11, p. 1217-1222 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
18 Citations (Scopus)
105 Downloads (Pure)

Next generation hemostatic materials based on NHS-Ester functionalized poly(2-oxazoline)s

Boerman, M. A., Roozen, E., Sanchez Fernandez, M. J., Keereweer, A. R., Félix Lanao, R. P., Bender, J. C. M. E., Hoogenboom, R., Leeuwenburgh, S. C. G., Jansen, J. A., van Goor, H. & van Hest, J. C. M., 14 Aug 2017, In : Biomacromolecules. 18, 8, p. 2529-2538 8.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
17 Citations (Scopus)
82 Downloads (Pure)

Peptide conjugates for biological applications

van Hest, J. C. M., Mar 2017, In : Bioconjugate Chemistry. 28, 3, p. 689-690 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
File
1 Citation (Scopus)
50 Downloads (Pure)

Science in a global community

van Hest, J. C. M., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V. M., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 279-281 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Self-assembling VHH-elastin-like peptides for photodynamic nanomedicine

Pille, J., van Lith, S. A. M., van Hest, J. C. M. & Leenders, W. P. J., 1 Apr 2017, In : Biomacromolecules. 18, 4, p. 1302-1310 9 p., 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
15 Citations (Scopus)
70 Downloads (Pure)

Self-propelled supramolecular nanomotors with temperature-responsive speed regulation

Tu, Y., Peng, F., Sui, X., Men, Y., White, P. B., van Hest, J. C. M. & Wilson, D. A., 9 May 2017, In : Nature Chemistry. 9, 5, p. 480-486 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
100 Citations (Scopus)
297 Downloads (Pure)

Self-regulated and temporal control of a "breathing" microgel mediated by enzymatic reaction

Che, H., Buddingh, B. C. & van Hest, J. C. M., 2 Oct 2017, In : Angewandte Chemie - International Edition. 56, 41, p. 12581-12585 5 p., 41.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
23 Citations (Scopus)
89 Downloads (Pure)

Stabilization of a virus-like particle and its application as a nanoreactor at physiological conditions

Schoonen, L., Maassen, S., Nolte, R. J. M. & van Hest, J. C. M., 13 Nov 2017, In : Biomacromolecules. 18, 11, p. 3492-3497 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Citations (Scopus)
53 Downloads (Pure)

Steering siglec–sialic acid interactions on living cells using bioorthogonal chemistry

Bull, C., Heise, T., van Hilten, N., Pijnenborg, J. F. A., Bloemendal, V., Gerrits, L., Kers-Rebel, E., Ritschel, T., den Brok, M. H. & Adema, G. J., 13 Mar 2017, In : Angewandte Chemie - International Edition. 56, 12, p. 3309-3313 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Sub-micron polymeric stomatocytes as promising templates for confined crystallization and diffraction experiments

Adawy, A., Amghouz, Z., van Hest, J. C. M. & Wilson, D. A., 13 Jul 2017, In : Small. 13, 28, p. 1-8 1700642.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
64 Downloads (Pure)

Supramolecular adaptive nanomotors with magnetotaxis behavior

Peng, F., Tu, Y., Men, Y., van Hest, J. C. M. & Wilson, D. A., 10 Feb 2017, In : Advanced Materials. 29, 6, p. 1-7 1604996.

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)
2 Downloads (Pure)
2016

A compartmentalized out-of-equilibrium enzymatic reaction network for sustained autonomous movement

Nijemeisland, M., Abdelmohsen, L. K. E. A., Huck, W. T. S., Wilson, D. A. & van Hest, J. C. M., 23 Nov 2016, In : ACS Central Science. 2, 11, p. 843-849 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
59 Citations (Scopus)
98 Downloads (Pure)

An integrated, peptide-based approach to site-specific protein immobilization for detection of biomolecular interactions

Kruis, I. C., Löwik, D. W. P. M., Boelens, W. C., van Hest, J. C. M. & Pruijn, G. J. M., 21 Sep 2016, In : Analyst. 141, 18, p. 5321-5328 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2 Downloads (Pure)

Click-MS: tagless protein enrichment using bioorthogonal chemistry for quantitative proteomics

Smits, A. H., Borrmann, A., Roosjen, M., Hest, van, J. C. M. & Vermeulen, M., 19 Sep 2016, In : ACS Chemical Biology. 11, 12, p. 3245–3250 6 p., 12.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
178 Downloads (Pure)

Editorial

van Hest, J. C. M., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V., 20 Jan 2016, In : Bioconjugate Chemistry. 27, 1, p. 1-2

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Shape characterization of polymersome morphologies via light scattering techniques

Abdelmohsen, L. K. E. A., Rikken, R. S. M., Christianen, P. C. M., van Hest, J. C. M. & Wilson, D. A., 19 Dec 2016, In : Polymer. 107, p. 445-449 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
1 Downloads (Pure)