• Postbus 513, Helix Building

    5600 MB Eindhoven

    Netherlands

  • De Groene Loper 3, Helix Building (STO 3.39)

    5612 AE Eindhoven

    Netherlands

Research Output 2008 2020

2018

Nanoemulsion-based delivery of fluorescent PARP inhibitors in mouse models of small cell lung cancer

Gonzales, J., Kossatz, S., Roberts, S., Pirovano, G., Brand, C., Pérez-Medina, C., Donabedian, P., de la Cruz, M. J., Mulder, W. J. M. & Reiner, T., 24 Oct 2018, In : Bioconjugate Chemistry. 29, 11, p. 3776-3782 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Small Cell Lung Carcinoma
Half-Life
Administrative data processing
Poly(ADP-ribose) Polymerases
Cells
16 Citations (Scopus)

Nanoreactors for green catalysis

De Martino, M. T., Abdelmohsen, L. K. E. A., Rutjes, F. P. J. T., van Hest, J. C. M. & Hessel, V., 29 Mar 2018, In : Beilstein Journal of Organic Chemistry. 14, p. 716–733

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoreactors
Catalysis
Industrial chemicals
Dendrimers
Micelles
1 Citation (Scopus)
Hepcidins
Biomarkers
Assays
formic acid
Proteins
4 Citations (Scopus)

Parasitic behavior of self-replicating molecules

Altay, M., Altay, Y. & Otto, S., 6 Aug 2018, In : Angewandte Chemie - International Edition. 57, 33, p. 10564-10568

Research output: Contribution to journalArticleAcademicpeer-review

Catalysis
Molecules
4 Citations (Scopus)

PH-induced transformation of biodegradable multilamellar nanovectors for enhanced tumor penetration

Cao, S., Abdelmohsen, L. K. E. A., Shao, J., van den Dikkenberg, J., Mastrobattista, E., Williams, D. S. & van Hest, J. C. M., 20 Nov 2018, In : ACS Macro Letters. 7, 11, p. 1394-1399 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tumors
Ethylene Glycol
Surface charge
Ethylene glycol
Hydration
3 Citations (Scopus)

Polymers at the interface with biology

Deming, T. J., Klok, H. A., Armes, S. P., Becker, M. L., Champion, J. A., Chen, E. Y. X., Heilshorn, S. C., van Hest, J. C. M., Irvine, D. J., Johnson, J. A., Kiessling, L. L., Maynard, H. D., De La Cruz, M. O., Sullivan, M. O., Tirrell, M. V., Anseth, K. S., Lecommandoux, S., Percec, S., Zhong, Z. & Albertsson, A. C., 13 Aug 2018, In : Biomacromolecules. 19, 8, p. 3151-3162 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Polymers
5 Citations (Scopus)

Polymorphism in benzene-1,3,5-tricarboxamide supramolecular assemblies in water: a subtle trade-off between structure and dynamics

Matsumoto, N. M., Lafleur, R. P. M., Lou, X., Shih, K. C., Wijnands, S. P. W., Guibert, C., van Rosendaal, J. W. A. M., Voets, I. K., Palmans, A. R. A., Lin, Y. & Meijer, E. W., 17 Oct 2018, In : Journal of the American Chemical Society. 140, 41, p. 13308-13316 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanotubes
Polymorphism
Benzene
Water
Temperature
7 Citations (Scopus)

Quaternary structure influences the peroxidase activity of peroxiredoxin 3

Yewdall, N. A., Peskin, A. V., Hampton, M. B., Goldstone, D. C., Pearce, F. G. & Gerrard, J. A., 4 Mar 2018, In : Biochemical and Biophysical Research Communications. 497, 2, p. 558-563 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Peroxiredoxin III
Dimers
Peroxidase
Peroxiredoxins
Self assembly
1 Citation (Scopus)

Residue-specific incorporation of noncanonical amino acids for protein engineering

van Eldijk, M. B. & van Hest, J. C. M., 2018, Noncanonical amino acids: methods and protocols. Lemke, E. A. (ed.). New York: Humana Press, p. 137-145 9 p. (Methods in Molecular Biology; vol. 1728)

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Protein Engineering
Alkynes
Azides
Amino Acids
Cycloaddition Reaction
12 Citations (Scopus)

Self-assembled nanoreactors based on peptides and proteins

Timmermans, S. B. P. E. & van Hest, J. C. M., 1 May 2018, In : Current Opinion in Colloid and Interface Science. 35, p. 26-35 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Nanoreactors
Peptides
peptides
proteins
Proteins
1 Citation (Scopus)

Self-assembly and stabilization of hybrid cowpea chlorotic mottle virus particles under nearly physiological conditions

Timmermans, S. B. P. E., Vervoort, D. F. M., Schoonen, L., Nolte, R. J. M. & van Hest, J. C. M., 1 Nov 2018, In : Chemistry - An Asian Journal. 13, 22, p. 3518-3525

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Viruses
Self assembly
Stabilization
Elastin
Capsid Proteins
4 Citations (Scopus)

Self-assembly of toroidal proteins explored using native mass spectrometry

Yewdall, N. A., Allison, T. M., Pearce, F. G., Robinson, C. V. & Gerrard, J. A., 1 Jan 2018, In : Chemical Science. 9, 28, p. 6099-6106 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Peroxiredoxins
Self assembly
Mass spectrometry
Nanotechnology
Proteins
2 Citations (Scopus)

Strain-stiffening in dynamic supramolecular fiber networks

Fernández-Castaño Romera, M., Lou, X., Schill, J., ter Huurne, G., Fransen, P. P. K. H., Voets, I. K., Storm, C. & Sijbesma, R. P., 19 Dec 2018, In : Journal of the American Chemical Society. 140, 50, p. 17547-17555 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hydrogels
Stress Fibers
Sonication
Fibers
Rheology
10 Citations (Scopus)

Supramolecular copolymerization as a strategy to control the stability of self-assembled nanofibers

Thota, B. N. S., Lou, X., Bochicchio, D., Paffen, T. F. E., Lafleur, R. P. M., van Dongen, J. L. J., Ehrmann, S., Haag, R., Pavan, G. M., Palmans, A. R. A. & Meijer, E. W., 4 Jun 2018, In : Angewandte Chemie - International Edition. 57, 23, p. 6843-6847

Research output: Contribution to journalArticleAcademicpeer-review

Nanofibers
Copolymerization
Polymers
Copolymers
Monomers
2 Citations (Scopus)

Temperature-induced collapse of elastin-like peptides studied by 2DIR spectroscopy

Selig, O., da Cunha, A. M. D. C. V., van Eldijk, M. B., van Hest, J. C. M., Jansen, T. L. C., Bakker, H. J. & Rezus, Y. L. A., 1 Aug 2018, In : Journal of Physical Chemistry B. 122, 34, p. 8243-8254 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
elastin
Elastin
Peptides
peptides
Spectroscopy
7 Citations (Scopus)

The hallmarks of living systems: Towards creating artificial cells

Amy Yewdall, N., Mason, A. F. & Van Hest, J. C. M., 6 Oct 2018, In : Interface Focus. 8, 5, 15 p., 20180023

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Artificial Cells
Earth (planet)
Biological Phenomena
Automatic Data Processing
Transplantation

Using pulse electric fields to improve permeabilization of DODAB vesicles

Rossi Batista, I., 23 Oct 2018, Eindhoven: Technische Universiteit Eindhoven. 53 p.

Research output: ThesisPd Eng ThesisAcademic

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: Approaches towards capsid rupture and gel repair

Schoenmakers, D. C., Schoonen, L., Rutten, M. G. T. A., Nolte, R. J. M., Rowan, A. E., van Hest, J. C. M. & Kouwer, P. H. J., 1 Jan 2018, In : Soft Matter. 14, 8, p. 1442-1448 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hydrogels
biomimetics
Biomimetics
viruses
Viruses
2017

A dibenzoazacyclooctyne as a reactive chain stopper for [2]rotaxanes

Hou, Z-Y., Yeniad, B., van Guyse, J., Woisel, P., Mullen, K. M., Rutjes, F. P. J. T., van Hest, J. C. M. & Hoogenboom, R., 8 Jun 2017, In : European Journal of Organic Chemistry. 21, p. 3107-3113 7 p., 21

Research output: Contribution to journalArticleAcademicpeer-review

Rotaxanes
cycloaddition
alkynes
naphthalene
ethers
2 Citations (Scopus)

Alternative application of an affinity purification tag: hexahistidines in ester hydrolysis

Schoonen, L., van Esterik, K. S., Zhang, C., Ulijn, R. V., Nolte, R. J. M. & van Hest, J. C. M., 7 Nov 2017, In : Scientific Reports. 7, 14772 , 9 p., 14772

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
His-His-His-His-His-His
Purification
Hydrolysis
Esters
Affinity chromatography
123 Citations (Scopus)

Artificial cells: synthetic compartments with life-like functionality and adaptivity

van Hest, J. C. M. & Buddingh, B. C., 17 Jan 2017, In : Accounts of Chemical Research. 50, 4, p. 769–777 4

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Membranes
Biochemistry
Chemotactic Factors
Metabolites
Metabolism
42 Citations (Scopus)

Bio-inks for 3D bioprinting: recent advances and future prospects

Donderwinkel, I., van Hest, J. C. M. & Cameron, N. R., 20 Aug 2017, In : Polymer Chemistry. 8, 31, p. 4451-4471 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Bioprinting
Printing
Ink
Polymers
Biocompatible Materials
3 Citations (Scopus)

Choice of capping group in tripeptide hydrogels influences viability in the three-dimensional cell culture of tumor spheroids

Wojciechowski, J. P., Martin, A. D., Mason, A. F., Fife, C. M., Sagnella, S. M., Kavallaris, M. & Thordarson, P., 1 Mar 2017, In : chempluschem. 82, 3, p. 383-389 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Cell culture
Tumors
Bearings (structural)
Gels
5 Citations (Scopus)

Coiled-coil mediated activation of oligo-arginine cell-penetrating peptides

Bode, S. A., Kruis, I. C., Adams, P. J. H. M., Boelens, W. C., Pruijn, G., van Hest, J. C. M. & Löwik, D. W. P. M., 2017, In : ChemBioChem. 18, 2, p. 185–188 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cell-Penetrating Peptides
Leucine Zippers
Arginine
Chemical activation
Peptides
5 Citations (Scopus)

Continuous fabrication of polymeric vesicles and nanotubes with fluidic channe

Peng, F., Deng, N-N., Tu, Y., van Hest, J. C. M. & Wilson, D. A., 21 Apr 2017, In : Nanoscale. 9, 15, p. 4875-4880 15

Research output: Contribution to journalArticleAcademicpeer-review

Polystyrenes
Fluidics
Phase boundaries
Platinum
Laminar flow
10 Citations (Scopus)

Controlling the morphology of copolymeric vectors for next generation nanomedicine

Williams, D. S., Pijpers, I. A. B., Ridolfo, R. & van Hest, J. C. M., 10 Aug 2017, In : Journal of Controlled Release. 259, 10 august 2016, p. 29-39

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanomedicine
Research
In Vitro Techniques
17 Citations (Scopus)

Dynamic diversity of synthetic supramolecular polymers in water as revealed by hydrogen/deuterium exchange

Lou, X., Lafleur, R. P. M., Leenders, C. M. A., Schoenmakers, S. M. C., Matsumoto, N. M., Baker, M. B., van Dongen, J. L. J., Palmans, A. R. A. & Meijer, E. W., 15 May 2017, In : Nature Communications. 8, 8 p., 15420

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Deuterium
deuterium
Hydrogen
Polymers
Water
1 Citation (Scopus)

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 282 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
1 Citation (Scopus)

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 21 Feb 2017, In : ACS Macro Letters. 6, 2, p. 144 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 14 Feb 2017, In : Macromolecules. 50, 3, p. 713 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 13 Feb 2017, In : Biomacromolecules. 18, 2, p. 315 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 8 Feb 2017, In : Chemical Reviews. 117, 3, p. 900 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
7 Citations (Scopus)

Evaluation of dextran(ethylene glycol) hydrogel films for giant unilamellar lipid vesicle production and their application for the encapsulation of polymersomes

Mora, N. L., Gao, Y., Gutierrez, M. G., Peruzzi, J., Bakker, I., Peters, R. J. R. W., Siewert, B., Bonnet, S., Kieltyka, R. E., van Hest, J. C. M., Malmstadt, N. & Kros, A., 4 Sep 2017, In : Soft Matter. 13, 33, p. 5580-5588 33

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Unilamellar Liposomes
dextrans
Ethylene Glycol
Dextrans
Encapsulation
5 Citations (Scopus)

Expansion of the assembly of cowpea chlorotic mottle virus towards non-native and physiological conditions

Schoonen, L., Maas, R. J. M., Nolte, R. J. M. & van Hest, J. C. M., 17 Aug 2017, In : Tetrahedron. 73, 33, p. 4968-4971 33

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bromovirus
Viruses
Elastin
Capsid Proteins
Peptides
20 Citations (Scopus)

Formation of non-spherical polymersomes driven by hydrophobic directional aromatic perylene interactions

Wong, C. K., Mason, A. F., Stenzel, M. H. & Thordarson, P., 1 Dec 2017, In : Nature Communications. 8, 1, 1240

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Perylene
Polymers
Synthetic Biology
shape control
membrane structures
23 Citations (Scopus)

Hierarchical self-assembly of a copolymer-stabilized coacervate protocell

Mason, A. F., Buddingh, B. C., Williams, D. S. & van Hest, J. C. M., 6 Dec 2017, In : Journal of the American Chemical Society. 139, 48, p. 17309-17312 4 p., 48

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Artificial Cells
Self assembly
Copolymers
Membranes
Biopolymers
18 Citations (Scopus)

Legomedicine - a versatile chemo-enzymatic approach for the preparation of targeted dual-labeled llama antibody-nanoparticle conjugates

van Lith, S. A. M., van Duijnhoven, S. M. J., Navis, A. C., Leenders, W. P. J., Dolk, E., Wennink, J. W. H., Nostrum, van, C. F. & van Hest, J. C. M., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 539-548 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
New World Camelids
Antibodies
Nanoparticles
Tail
Single-Domain Antibodies
12 Citations (Scopus)

Morphology under control: engineering biodegradable stomatocytes

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Williams, D. S. & van Hest, J. C. M., 1 Nov 2017, In : ACS Macro Letters. 6, 11, p. 1217-1222 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polyethylene glycols
Membranes
Copolymers
Dialysis
Solvation
13 Citations (Scopus)

Next generation hemostatic materials based on NHS-Ester functionalized poly(2-oxazoline)s

Boerman, M. A., Roozen, E., Sanchez Fernandez, M. J., Keereweer, A. R., Félix Lanao, R. P., Bender, J. C. M. E., Hoogenboom, R., Leeuwenburgh, S. C. G., Jansen, J. A., van Goor, H. & van Hest, J. C. M., 1 Aug 2017, In : Biomacromolecules. 18, 8, p. 2529-2538 8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hemostatics
Esters
Polymers
Polyethylene glycols
Blood
1 Citation (Scopus)

Peptide conjugates for biological applications

van Hest, J. C. M., 23 Feb 2017, In : Bioconjugate Chemistry. 28, 3, p. 689-690 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
File
9 Citations (Scopus)

Polymersomes as protocellular constructs

Mason, A. F. & Thordarson, P., 1 Jan 2017, In : Journal of Polymer Science, Part A: Polymer Chemistry. 55, 23, p. 3817-3825 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Polymers
Scaffolds
Membranes
Engineers

Quantitative assessment of prosthetic valve regurgitation after TAVI by angiography and cardiac magnetic resonance imaging

Abdelghani, M., Abdel-Wahab, M., Miyazaki, Y., Holy, E., Merten, C., Zachow, D., Tonino, P., Rutten, M., van de Vosse, F. N., Morel, M. A., Onuma, Y., Serruys, P., Richardt, G. & Soliman, O., Aug 2017, In : European Heart Journal. 38, Issue suppl_1, p. 623-623

Research output: Contribution to journalMeeting AbstractAcademic

Open Access

Science in a global community

van Hest, J. C. M., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V. M., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 279-281 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
11 Citations (Scopus)

Self-assembling VHH-elastin-like peptides for photodynamic nanomedicine

Pille, J., van Lith, S. A. M., van Hest, J. C. M. & Leenders, W. P. J., 1 Apr 2017, In : Biomacromolecules. 18, 4, p. 1302-1310 4

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Medical nanotechnology
Elastin
Epidermal Growth Factor Receptor
Peptides
Nanoparticles
79 Citations (Scopus)

Self-propelled supramolecular nanomotors with temperature-responsive speed regulation

Tu, Y., Peng, F., Sui, X., Men, Y., White, P. B., van Hest, J. C. M. & Wilson, D. A., 9 May 2017, In : Nature Chemistry. 9, 5, p. 480-486

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Micromotors
Nanosystems
Brushes
Brakes
Fuel consumption
15 Citations (Scopus)

Self-regulated and temporal control of a "breathing" microgel mediated by enzymatic reaction

Che, H., Buddingh, B. C. & van Hest, J. C. M., 2 Oct 2017, In : Angewandte Chemie - International Edition. 56, 41, p. 12581-12585 41

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Urease
Enzymes
Fluorescence
Switches
Feedback
9 Citations (Scopus)

Stabilization of a virus-like particle and its application as a nanoreactor at physiological conditions

Schoonen, L., Maassen, S., Nolte, R. J. M. & van Hest, J. C. M., 20 Jun 2017, In : Biomacromolecules. 18, 11, p. 3492-3497 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoreactors
Viruses
Stabilization
Enzymes
Muramidase
1 Citation (Scopus)

Sub-micron polymeric stomatocytes as promising templates for confined crystallization and diffraction experiments

Adawy, A., Amghouz, Z., van Hest, J. C. M. & Wilson, D. A., 13 Jul 2017, In : Small. 13, 28, p. 1-8 1700642

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Crystallization
Crystallography
Diffraction
Nanoparticles
Nanocrystals
25 Citations (Scopus)

Supramolecular adaptive nanomotors with magnetotaxis behavior

Peng, F., Tu, Y., Men, Y., van Hest, J. C. M. & Wilson, D. A., 10 Feb 2017, In : Advanced Materials. 29, 6, p. 1-7 1604996

Research output: Contribution to journalArticleAcademicpeer-review

2016
51 Citations (Scopus)

A compartmentalized out-of-equilibrium enzymatic reaction network for sustained autonomous movement

Nijemeisland, M., Abdelmohsen, L. K. E. A., Huck, W. T. S., Wilson, D. A. & van Hest, J. C. M., 23 Nov 2016, In : ACS Central Science. 2, 11, p. 843-849 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File