• Postbus 513, Helix Building

    5600 MB Eindhoven

    Netherlands

  • De Groene Loper 3, Helix Building (STO 3.39)

    5612 AE Eindhoven

    Netherlands

Research Output

A block copolymer for functionalisation of polymersome surfaces

van Dongen, S. F. M., Nallani, M., Schoffelen, S., Cornelissen, J. J. L. M., Nolte, R. J. M. & van Hest, J. C. M., 18 Feb 2008, In : Macromolecular Rapid Communications. 29, 4, p. 321-325 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

68 Citations (Scopus)

Accelerated living cationic ring-opening polymerization of a methyl ester functionalized 2-oxazoline monomer

Bouten, P. J. M., Hertsen, D., Vergaelen, M., Monnery, B. D., Boerman, M. A., Goossens, H., Catak, S., van Hest, J. C. M., van Speybroeck, V. & Hoogenboom, R., 28 Jan 2015, In : Polymer Chemistry. 6, 4, p. 514-518 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)

A compartmentalized out-of-equilibrium enzymatic reaction network for sustained autonomous movement

Nijemeisland, M., Abdelmohsen, L. K. E. A., Huck, W. T. S., Wilson, D. A. & van Hest, J. C. M., 23 Nov 2016, In : ACS Central Science. 2, 11, p. 843-849 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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59 Citations (Scopus)
98 Downloads (Pure)

Adaptive polymeric assemblies for applications in biomimicry and nanomedicine

Altay, Y., Che, H., Cao, S., Abdelmohsen, L. & van Hest, J., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4053-4064 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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2 Citations (Scopus)
30 Downloads (Pure)

Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Xia, Y., Cao, S., Williams, D. S., Meng, F., van Hest, J. C. M. & Zhong, Z., 1 Dec 2018, In : Advanced Therapeutics. 1, 8, 14 p., 1800068.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Downloads (Pure)

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 1 Sep 2019, In : ChemNanoMat. 5, 9, p. 1092-1109 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Citations (Scopus)
49 Downloads (Pure)

A dibenzoazacyclooctyne as a reactive chain stopper for [2]rotaxanes

Hou, Z-Y., Yeniad, B., van Guyse, J., Woisel, P., Mullen, K. M., Rutjes, F. P. J. T., van Hest, J. C. M. & Hoogenboom, R., 8 Jun 2017, In : European Journal of Organic Chemistry. 2017, 21, p. 3107-3113 7 p., 21.

Research output: Contribution to journalArticleAcademicpeer-review

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

De Jong, E., Williams, D. S., Abdelmohsen, L. K. E. A., van Hest, J. C. M. & Zuhorn, I. S., 10 Nov 2018, In : Journal of Controlled Release. 289, p. 14-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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1 Citation (Scopus)
38 Downloads (Pure)

Alendronate-functionalized poly(2-oxazoline)s with tunable affinity for calcium cations

Sánchez-Fernández, M. J., Immers, M. R., Félix Lanao, R. P., Yang, F., Bender, J. C. M. E., Mecinović, J., Leeuwenburgh, S. C. G. & van Hest, J. C. M., 12 Aug 2019, In : Biomacromolecules. 20, 8, p. 2913-2921 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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11 Downloads (Pure)

Alternative application of an affinity purification tag: hexahistidines in ester hydrolysis

Schoonen, L., van Esterik, K. S., Zhang, C., Ulijn, R. V., Nolte, R. J. M. & van Hest, J. C. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 14772.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
84 Downloads (Pure)

An integrated, peptide-based approach to site-specific protein immobilization for detection of biomolecular interactions

Kruis, I. C., Löwik, D. W. P. M., Boelens, W. C., van Hest, J. C. M. & Pruijn, G. J. M., 21 Sep 2016, In : Analyst. 141, 18, p. 5321-5328 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2 Downloads (Pure)

A revised modular approach to (–)-trans-Δ 8 -THC and derivatives through late-stage Suzuki–Miyaura cross-coupling reactions

Bloemendal, V. R. L. J., Sondag, D., Elferink, H., Boltje, T. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 31 Mar 2019, In : European Journal of Organic Chemistry. 2019, 12, p. 2289-2296 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Citations (Scopus)
30 Downloads (Pure)

Artificial cells: synthetic compartments with life-like functionality and adaptivity

van Hest, J. C. M. & Buddingh, B. C., 17 Jan 2017, In : Accounts of Chemical Research. 50, 4, p. 769–777 9 p., 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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146 Citations (Scopus)
140 Downloads (Pure)

ATP-mediated transient behavior of stomatocyte nanosystems

Che, H., Zhu, J., Song, S., Mason, A. F., Cao, S., Pijpers, I. A. B., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 9 Sep 2019, In : Angewandte Chemie - International Edition. 58, 37, p. 13113-13118 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
3 Downloads (Pure)

Biodegradable, drug-loaded nanovectors via direct hydration as a new platform for cancer therapeutics

Ridolfo, R., Ede, B. C., Diamanti, P., White, P. B., Perriman, A. W., van Hest, J. C. M., Blair, A. & Williams, D. S., 9 Aug 2018, In : Small. 14, 32, 10 p., 1703774.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
51 Downloads (Pure)

Biodegradable synthetic organelles demonstrate ROS shielding in human-complex-I-deficient fibroblasts

van Oppen, L. M. P. E., Abdelmohsen, L. K. E. A., van Emst-de Vries, S. E., Welzen, P. L. W., Wilson, D. A., Smeitink, J. A. M., Koopman, W. J. H., Brock, R., Willems, P. H. G. M., Williams, D. S. & van Hest, J. C. M., 25 Jul 2018, In : ACS Central Science. 4, 7, p. 917-928 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
12 Citations (Scopus)
83 Downloads (Pure)

Bio-inks for 3D bioprinting: recent advances and future prospects

Donderwinkel, I., van Hest, J. C. M. & Cameron, N. R., 20 Aug 2017, In : Polymer Chemistry. 8, 31, p. 4451-4471 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

68 Citations (Scopus)

Biomimicry of Cellular Motility and Communication Based on Synthetic Soft-Architectures

Wang, L., Song, S., van Hest, J., Abdelmohsen, L. K. E. A., Huang, X. & Sánchez, S., 6 Apr 2020, In : Small.

Research output: Contribution to journalReview articleAcademicpeer-review

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 6 Mar 2019, In : Advanced Science. 6, 5, 8 p., 1801678.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
32 Downloads (Pure)

Bone-adhesive materials: clinical requirements, mechanisms of action, and future perspective

Sánchez-Fernández, M. J., Hammoudeh, H., Félix Lanao, R. P., van Erk, M., van Hest, J. C. M. & Leeuwenburgh, S. C. G., 22 Feb 2019, In : Advanced Materials Interfaces. 6, 4, 11 p., 1802021.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
38 Downloads (Pure)

CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice

Zhong, Y., Meng, F., Zhang, W., Li, B., van Hest, J. C. M. & Zhong, Z., 10 Apr 2020, In : Journal of Controlled Release. 320, p. 421-430 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks

Dubuc, E., Pieters, P. A., van der Linden, A. J., van Hest, J. C. M., Huck, W. T. S. & de Greef, T. F. A., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 72-80 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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10 Citations (Scopus)
74 Downloads (Pure)

Chemical tools and materials for Biological/Medicinal applications

Yan, X. & van Hest, J. C. M., 16 Nov 2018, In : Chemistry - An Asian Journal. 13, 22, p. 3331-3332 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
6 Citations (Scopus)

Chemoenzymatic synthesis of sialic acid derivatives using immobilized N-acetylneuraminate lyase in a continuous flow reactor

Bloemendal, V. R. L. J., Moons, S. J., Heming, J. J. A., Chayoua, M., Niesink, O., van Hest, J. C. M., Boltje, T. J. & Rutjes, F. P. J. T., 6 Jun 2019, In : Advanced Synthesis & Catalysis. 361, 11, p. 2443-2447 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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5 Downloads (Pure)

Click-MS: tagless protein enrichment using bioorthogonal chemistry for quantitative proteomics

Smits, A. H., Borrmann, A., Roosjen, M., Hest, van, J. C. M. & Vermeulen, M., 19 Sep 2016, In : ACS Chemical Biology. 11, 12, p. 3245–3250 6 p., 12.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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8 Citations (Scopus)
178 Downloads (Pure)

Click to enter: activation of oligo-arginine cell-penetrating peptides by bioorthogonal tetrazine ligations

Bode, S. A., Timmermans, S. B. P. E., Eising, S., van Gemert, S. P. W., Bonger, K. M. & Löwik, D. W. P. M., 21 Jan 2019, In : Chemical Science. 10, 3, p. 701-705 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
35 Downloads (Pure)

Coiled-coil mediated activation of oligo-arginine cell-penetrating peptides

Bode, S. A., Kruis, I. C., Adams, P. J. H. M., Boelens, W. C., Pruijn, G., van Hest, J. C. M. & Löwik, D. W. P. M., 17 Jan 2017, In : ChemBioChem. 18, 2, p. 185–188 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
112 Downloads (Pure)

Compartmentalized cross-linked enzymatic nano -aggregates (c -CLE n A) for efficient in-flow biocatalysis

de Martino, M. T., Tonin, F., Yewdall, N. A., Abdelghani, M., Williams, D. S., Hanefeld, U., Rutjes, F. P. J. T., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 14 Mar 2020, In : Chemical Science. 11, 10, p. 2765-2769 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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8 Downloads (Pure)

Continuous fabrication of polymeric vesicles and nanotubes with fluidic channels

Peng, F., Deng, N-N., Tu, Y., van Hest, J. C. M. & Wilson, D. A., 21 Apr 2017, In : Nanoscale. 9, 15, p. 4875-4880 6 p., 15.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Controlling the morphology of copolymeric vectors for next generation nanomedicine

Williams, D. S., Pijpers, I. A. B., Ridolfo, R. & van Hest, J. C. M., 10 Aug 2017, In : Journal of Controlled Release. 259, 10 august 2016, p. 29-39 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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16 Citations (Scopus)
112 Downloads (Pure)

Copolymer-stabilized coacervate microdroplets as multicompartmentalized artificial cells

Mason, A., Abdelmohsen, L., Yewdall, N. A., Buddingh, B., Williams, D. & van Hest, J., Aug 2018, In : Abstracts of Papers of the American Chemical Society. 1 p., BM09.12.07.

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
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31 Downloads (Pure)

Development of morphologically discrete PEG-PDLLA nanotubes for precision nanomedicine

Wauters, A. C., Pijpers, I. A. B., Mason, A. F., Williams, D. S., Tel, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 14 Jan 2019, In : Biomacromolecules. 20, 1, p. 177-183 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
76 Downloads (Pure)

Dithioacetal-mechanized mesoporous nanosensor for Hg(II) determination

Jimenez-Falcao, S., Villalonga, A., Parra-Nieto, J., Llopis-Lorente, A., Martinez-Ruiz, P., Martinez-Mañez, R. & Villalonga, R., 1 May 2020, In : Microporous and Mesoporous Materials. 297, 7 p., 110054.

Research output: Contribution to journalArticleAcademicpeer-review

Dynamic assembly of micellar mesostructures

Altay, Y., Pijpers - Welzen, I., Abdelmohsen, L. & van Hest, J., 28 Oct 2019, In : ChemSystemsChem. 2, 2, 5 p., e1900049.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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2 Downloads (Pure)

Editorial

van Hest, J. C. M., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V., 20 Jan 2016, In : Bioconjugate Chemistry. 27, 1, p. 1-2

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial 2018

van Hest, J., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V. M., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 21 Feb 2017, In : ACS Macro Letters. 6, 2, p. 144 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
2 Citations (Scopus)

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 14 Feb 2017, In : Macromolecules. 50, 3, p. 713 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 13 Feb 2017, In : Biomacromolecules. 18, 2, p. 315 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Editorial for virtual issue on polymer bioconjugates in biology and medicine

van Hest, J. C. M., Sumerlin, B., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 15 Feb 2017, In : Bioconjugate Chemistry. 28, 2, p. 282 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
1 Citation (Scopus)

Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine

van Hest, J. C. M., Sumerlin, B. S., Anseth, K. S., Shoichet, M. & Hammes-Schiffer, S., 8 Feb 2017, In : Chemical Reviews. 117, 3, p. 900 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Effect of formulation and processing parameters on the size of mPEG-b-p(HPMA-Bz) polymeric micelles

Bagheri, M., Bresseleers, J., Varela-Moreira, A., Sandre, O., Meeuwissen, S. A., Schiffelers, R. M., Metselaar, J. M., Van Nostrum, C. F., van Hest, J. C. M. & Hennink, W. E., 18 Dec 2018, In : Langmuir. 34, 50, p. 15495-15506 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
1 Downloads (Pure)

Engineering interactive artificial cells

Buddingh, B. C., 20 Jan 2020, Eindhoven: Technische Universiteit Eindhoven. 178 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

12 Downloads (Pure)

Engineering protein-based nanoparticle conjugates for nanomedicine applications

van Hest, J., Pille, J., Abdelghani, M., Timmermans, S., Vervoort, D. & Pretto, C., 19 Aug 2018, 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond .

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Erythrocyte membrane modified janus polymeric motors for thrombus therapy

Shao, J., Abdelghani, M., Shen, G., Cao, S., Williams, D. S. & van Hest, J. C. M., 22 May 2018, In : ACS Nano. 12, 5, p. 4877-4885 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Citations (Scopus)
61 Downloads (Pure)

Evaluation of dextran(ethylene glycol) hydrogel films for giant unilamellar lipid vesicle production and their application for the encapsulation of polymersomes

Mora, N. L., Gao, Y., Gutierrez, M. G., Peruzzi, J., Bakker, I., Peters, R. J. R. W., Siewert, B., Bonnet, S., Kieltyka, R. E., van Hest, J. C. M., Malmstadt, N. & Kros, A., 4 Sep 2017, In : Soft Matter. 13, 33, p. 5580-5588 9 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
84 Downloads (Pure)

Expansion of the assembly of cowpea chlorotic mottle virus towards non-native and physiological conditions

Schoonen, L., Maas, R. J. M., Nolte, R. J. M. & van Hest, J. C. M., 17 Aug 2017, In : Tetrahedron. 73, 33, p. 4968-4971 4 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
86 Downloads (Pure)

Feedback-induced temporal control of “breathing” polymersomes to create self-adaptive nanoreactors

Che, H., Cao, S. & van Hest, J. C. M., 25 Apr 2018, In : Journal of the American Chemical Society. 140, 16, p. 5356–5359 4 p., 16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
42 Citations (Scopus)
109 Downloads (Pure)

Hierarchical self-assembly of a copolymer-stabilized coacervate protocell

Mason, A. F., Buddingh, B. C., Williams, D. S. & van Hest, J. C. M., 6 Dec 2017, In : Journal of the American Chemical Society. 139, 48, p. 17309-17312 4 p., 48.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
29 Citations (Scopus)
117 Downloads (Pure)

Hybrid bio/supra-molecular polymers as programmable nano-architectures

Magdalena Estirado, E., 13 Jan 2020, Eindhoven: Technische Universiteit Eindhoven. 193 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

4 Downloads (Pure)