Sleep Medicine

van Gilst, Merel M. (Content manager)
van der Hout-van der Jagt, M.B. (Beatrijs) (Content manager)

Eindhoven MedTech Innovation Center

Impact: Research Topic/Theme (at group level)

Description of impact

ADVANCED SLEEP MONITORING

Sleep is an essential behavior, takingup about approximately one third of our lives. Therefore, it is not surprisingthat sleep disorders have a profound impact on quality of life.

Both subjective symptoms of sleepdisorders as well as objective indicators of sleep quality are not constant,and can vary considerably from night to night. In current clinical practice however, sleep monitoring usually consistsof only one night recording of physiological signals such as brain activity,heart rate and respiration. Moreover, current diagnostic techniques assess onlya small part of the underlying pathophysiology, still using EEG-basedpolysomnographic measurements developed in the '60s. Therefore, there is astrong need for advanced sleep monitoring techniques that can obtain bothsubjective and objective data over the long term in patient friendly (at home)settings, and assess disorders on a deeper pathophysiological level.

Within theBM/d Research Lab, we are intensively working together withthe Centerfor Sleep Medicine Kempenhaeghe to create a next generation ‘toolbox of sleep medicine’, improving the careprocess from screening, diagnosis, treatment selection towards outcomemonitoring.

Research approaches include advancedanalysis techniques to extract more information from current diagnostictechnologies such as polysomnography. Moreover, new technologies are developedand validated to fundamentally upgrade sleep monitoring and diagnostics. Theseinclude non-obtrusive ways of long-term sleep assessment, for example based oncardiorespiratory sleep scoring. Morepathophysiological insights are gained from new ways to quantify respiratoryeffort. The long-term tracking of subjective sleep symptoms is combined withthese objective measurements. Importantly, sleep is regarded as a ’24-hour phenomenon’, implying thatassessment of daytime symptoms and behavior is an essential part of thediagnostic process.

Category of impact	Research Topic/Theme (at group level)

Press / Media

Slapen zonder plakkers

Press/Media: Public Engagement Activities

Gewoon een slechte nacht, of echt een slaapstoornis

Press/Media: Public Engagement Activities

Slapen met een app.

Press/Media: Public Engagement Activities

Waarom kan je je niet herinneren dat je in slaap bent gevallen?

Press/Media: Public Engagement Activities

Raadsel van de slaap

Press/Media: Public Engagement Activities

Voor opsporen slaapapneu is [dit] wellicht niet meer nodig

Press/Media: Expert Comment

Mensen met een slaapstoornis hebben niks aan gadgets.

Press/Media: Public Engagement Activities

Slaaparts werkt aan simpeler maken van onderzoek naar ernstige slaapstoornissen.

Press/Media: Public Engagement Activities

Kun je slaaptekort in één nacht inhalen?

Press/Media: Research

Detecting Sleep Apnea in Your Own Bed: Eindhoven University of Technology

Press/Media: Expert Comment

Detecting sleep apnea in your own bed

Press/Media: Expert Comment

Wearables voor slaaponderzoek?

Press/Media: Public Engagement Activities

Slaapapneu opsporen vanuit je eigen bed

Press/Media: Expert Comment

Technische snufjes tegen slecht slapen.

Press/Media: Public Engagement Activities

Innovatie in de slaapdiagnostiek.

Press/Media: Public Engagement Activities

Studie naar invloed Airport op nachtrust

Press/Media: Research

Apneu beu

Press/Media: Expert Comment

Don't take changing the clocks too lightly

Press/Media: Expert Comment

Lichtschakelaar zet bij muizen REM slaap aan.

Press/Media: Public Engagement Activities

Nieuwe meetmethode maakt ervaring van slapeloosheid beter zichtbaar.

Press/Media: Public Engagement Activities

Slaap.

Press/Media: Public Engagement Activities

Wat is slaapmisperceptie?

Press/Media: Public Engagement Activities

Research Output

'The clocks that time us'--circadian rhythms in neurodegenerative disorders

Research output: Contribution to journal › Article › Academic › peer-review

On the impact of arousals on the performance of sleep and wake classification using actigraphy

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Spectral boundary adaptation on heart rate variability for sleep and wake classification

Research output: Contribution to journal › Article › Academic › peer-review

Sinus or not: a new beat detection algorithm based on a pulse morphology quality index to extract normal sinus rhythm beats from wrist-worn photoplethysmography recordings

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Research output: Contribution to journal › Article › Academic › peer-review

Recurrent neural network for classification of snoring and non-snoring sound events

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Poor sleep quality and fatigue but no excessive daytime sleepiness in myotonic dystrophy type 2

Research output: Contribution to journal › Article › Academic › peer-review

Using dynamic time warping for sleep and wake discrimination

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Impaired social functioning in children with narcolepsy

Research output: Contribution to journal › Article › Academic › peer-review

Effects of between- and within-subject variability on autonomic cardiorespiratory activity during sleep and their limitations on sleep staging : a multilevel analysis

Research output: Contribution to journal › Article › Academic › peer-review

Photoplethysmography beat detection and pulse morphology quality assessment for signal reliability estimation

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Full video pulse extraction

Research output: Contribution to journal › Article › Academic › peer-review

Unsupervised subject detection via remote PPG

Research output: Contribution to journal › Article › Academic › peer-review

FDG PET, dopamine transporter SPECT, and olfaction: Combining biomarkers in REM sleep behavior disorder

Research output: Contribution to journal › Article › Academic › peer-review

Heart rate variability-based sleep staging in healthy subjects and patients with sleep disorders

Research output: Contribution to journal › Meeting Abstract › Academic

Fully-automatic camera-based pulse-oximetry during sleep

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Analyzing respiratory effort amplitude for automated sleep stage classification

Research output: Contribution to journal › Article › Academic › peer-review

Publisher Correction: Enhanced food-related responses in the ventral medial prefrontal cortex in narcolepsy type 1 (Scientific Reports, (2018), 8, 1, (16391), 10.1038/s41598-018-34647-6)

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Brain glucose metabolism heterogeneity in idiopathic REM sleep behavior disorder and in Parkinson's disease

Research output: Contribution to journal › Article › Academic › peer-review

Automatic feature selection for sleep/wake classification with small data sets

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Estimation of the apnea-hypopnea index in a heterogeneous sleep-disordered population using optimised cardiovascular features

Research output: Contribution to journal › Article › Academic › peer-review

Sleep-cognition hypothesis in maritime pilots, what is the effect of long-term work-related poor sleep on cognition and amyloid accumulation in healthy middle-aged maritime pilots: methodology of a case-control study

Research output: Contribution to journal › Article › Academic › peer-review

Respiration amplitude analysis for REM and NREM sleep classification

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Parkinson's disease and turning in bed

Research output: Contribution to conference › Poster

On the relationship of arousals and artifacts in respiratory effort signals

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

What causes the differences in cardiac activity within and between subjects during sleep?

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

Hypocretin/orexin disturbances in neurological disorders

Research output: Contribution to journal › Article › Academic › peer-review

Phenotypes of sleeplessness: stressing the need for psychodiagnostics in the assessment of insomnia

Research output: Contribution to journal › Article › Academic › peer-review

Home sleep monitoring

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Modelling sleep onset misperception in insomnia

Research output: Contribution to journal › Article › Academic › peer-review

A novel low-complexity post-processing algorithm for precise QRS localization

Research output: Contribution to journal › Article › Academic › peer-review

Anxiety and mood disorders in narcolepsy: a case-control study

Research output: Contribution to journal › Article › Academic › peer-review

The impact of delayed sleep phase disorder on adolescents and their family

Research output: Contribution to journal › Article › Academic › peer-review

HLA associations in narcolepsy type 1 persist after the 2009 H1N1 pandemic

Research output: Contribution to journal › Article › Academic › peer-review

Automatic sleep staging using heart rate variability, body movements, and recurrent neural networks in a sleep disordered population

Research output: Contribution to journal › Article › Academic › peer-review

On the generalizability of ECG-based obstructive sleep apnea monitoring: merits and limitations of the Apnea-ECG database

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Actigraphy-based sleep/wake detection for insomniacs

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

V-awake: a visual analytics approach for correcting sleep predictions from deep learning models

Research output: Contribution to journal › Conference article › Academic › peer-review

A comparison of probabilistic classifiers for sleep stage classification

Research output: Contribution to journal › Article › Academic › peer-review

Time delay between cardiac and brain activity during sleep transitions

Research output: Contribution to journal › Article › Academic › peer-review

Combining HRV features for automatic arousal detection

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Measuring dissimilarity between respiratory effort signals based on uniform scaling for sleep staging

Research output: Contribution to journal › Article › Academic › peer-review

Gender effect found in the association between overnight breathing rate variation and reported sleep quality scores

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

Sleep apnea detection using time-delayed heart rate variability

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Sleep and wake classification with actigraphy and respiratory effort using dynamic warping

Research output: Contribution to journal › Article › Academic › peer-review

Autonomic cardiac activity in adults with short and long sleep onset latency

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Sleep EEG characteristics associated with sleep onset misperception

Research output: Contribution to journal › Article › Academic › peer-review

The influence of the length of awakenings on sleep onset misperception

Research output: Contribution to journal › Meeting Abstract › Academic

Between-laboratory and demographic effects on heart rate and its variability during sleep

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Sleep stage classification from heart-rate variability using long short-term memory neural networks

Research output: Contribution to journal › Article › Academic › peer-review

Improving sleep/wake detection via boundary adaptation for respiratory spectral features

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Video-based respiration monitoring with automatic region of interest detection

Research output: Contribution to journal › Article › Academic › peer-review

Multilevel interval coded scoring to assess the cardiovascular status of sleep apnea patients using oxygen saturation markers

Research output: Contribution to journal › Article › Academic › peer-review

Protocol of the SOMNIA project: an observational study to create a neurophysiological database for advanced clinical sleep monitoring

Research output: Contribution to journal › Article › Academic › peer-review

A mobile app for longterm monitoring of narcolepsy symptoms: design, development, and evaluation

Research output: Contribution to journal › Article › Academic › peer-review

Accelerometer-based quantitative analysis of axial nocturnal movements differentiates patients with Parkinson's disease, but not high-risk individuals, from controls

Research output: Contribution to journal › Article › Academic › peer-review

The distinguishing motor features of cataplexy: a study from video-recorded attacks

Research output: Contribution to journal › Article › Academic › peer-review

Automatic roI detection for camera-based pulse-rate measurement

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

The role of personality traits in insomnia

Research output: Contribution to journal › Article › Academic › peer-review

Recurrence quantification analysis across sleep stages

Research output: Contribution to journal › Article › Academic › peer-review

Home video monitoring system for neurodegenerative diseases based on commercial HD cameras

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Social responsiveness in pediatric narcolepsy patients

Research output: Contribution to journal › Meeting Abstract › Academic

Conceptions of sleep experience: a layman perspective

Research output: Contribution to journal › Article › Academic › peer-review

Time-frequency analysis of heart rate variability for sleep and wake classification

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

An interactive thought visualization tool for insomnia treatment

Research output: Contribution to journal › Article › Academic › peer-review

Sleep stage classification with ECG and respiratory effort

Research output: Contribution to journal › Article › Academic › peer-review

Cardiorespiratory sleep stage detection using conditional random fields

Research output: Contribution to journal › Article › Academic › peer-review

The effect of chronic sleep deprivation on cognition in healthy middle aged men

Research output: Contribution to journal › Meeting Abstract › Academic

Hands reaching out of dreamland : a haptic peripheral alarm clock

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Automatic detection of overnight deep sleep based on heart rate variability : a preliminary study

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Design and evaluation of a negotiation-based sleep scheduler app for insomnia treatment

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Detection of nocturnal slow wave sleep based on cardiorespiratory activity in healthy adults

Research output: Contribution to journal › Article › Academic › peer-review

On the analysis and classification of sleep stages from cardiorespiratory activity

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia

Research output: Contribution to journal › Article › Academic › peer-review

Self-dissimilarity of respiratory effort across sleep states and time

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

Exploring the Parkinson patients' perspective on home-based video recording for movement analysis: a qualitative study

Research output: Contribution to journal › Article › Academic › peer-review

Exploring the clinical features of narcolepsy type 1 versus narcolepsy type 2 from European Narcolepsy Network database with machine learning

Research output: Contribution to journal › Article › Academic › peer-review

Using advanced PPG analysis to study sleep architecture in insomnia

Research output: Contribution to conference › Poster

Modelling sleep onset misperception in insomnia

Research output: Contribution to journal › Meeting Abstract › Academic

Subjective sleep quality monitoring with the hypnos digital sleep diary: Evaluation of usability and user experience

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Estimating actigraphy from motion artifacts in ECG and respiratory effort signals

Research output: Contribution to journal › Article › Academic › peer-review

Enhanced food-related responses in the ventral medial prefrontal cortex in narcolepsy type 1

Research output: Contribution to journal › Article › Academic › peer-review

Modelling sleep state misperception at sleep onset

Research output: Contribution to journal › Meeting Abstract › Academic

Single element remote-PPG

Research output: Contribution to journal › Article › Academic › peer-review

Robust two-dimensional pressure sensing mattress based on optical coupling between crossing polymer optical fibres

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Improving sleep/wake classification with recurrence quantification analysis features

Research output: Contribution to journal › Article › Academic › peer-review

Lying awake at night: cardiac autonomic activity in relation to sleep onset and maintenance

Research output: Contribution to journal › Article › Academic › peer-review

Correlations between overnight breathing rate variation and subjective sleep quality scores

Research output: Contribution to journal › Article › Academic › peer-review

Real-time two-dimensional pressure sensing for patient monitoring based on optical coupling between crossing polymer optical fibres

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Sleep Medicine

Description of impact

Related content

Press / Media

Research Output

Prizes

Activities