Description of impact
“Family-centered care innovations for the first 1000 days of life”The first 1000 days of
life start with conception and are followed by the prenatal(pregnancy),
delivery (child-birth), and neonatal (newborn) phases. All phases are very
different in nature and yield important needs and opportunities for
technology-based innovation. In the unique collaboration between hospital, university
and industry, e/MTIC focuses on non-invasive monitoring techniques and on
educational simulators. These focal points are intertwined via common work on
physiological models. They match naturally to the available expertise of the
partners and to several important wheels that are already in motion. Last but
not least, they foreshadow an important innovation potential, scientifically,
clinically, and commercially. All projects contribute to our family-centered
care innovation vision.
Our themes:
o Pregnancy monitoring:
Pregnancy and delivery are risky phases in the
life of mother and child. Key health risks include premature delivery and poor
placenta function, which are both potentially lethal to the fetus or can lead
to life-long disabilities. Current monitoring techniques leave much to be
desired: they frequently fail to detect critical risks yet also lead to many
unnecesary interventions. Moreover they are only sparsely available (20-week
echo, antenatal visits, delivery) so that risks that develop in between are
likely to go undetected. Our aim is to a) strongly improve the dependability of
pregnancy monitoring (especially Doppler ultrasound), and b) to make a step
towards continuous monitoring (by analyzing electrical signals recording on the
maternal abdomen).
o Neonatal monitoring & simulation:
The Neonatal Monitoring & Simulation program
line develops new techniques for safe and quiet care of the newborn,
facilitating family-centered care and mother-child bonding, in order to improve
patient outcome. We focus on the development of new parameters and on
unobtrusive measurement ways of these parameters. Moreover, we investigate
techniques for predictive monitoring using big data. To investigate the effects
of clinical interventions on neonatal outcome, we develop simulation
(mathematical and physical) models. The models are primarily used for the
formulation of hypotheses, that are then tested in a clinical setting.
o Family health:
In the Parents & Kids program line we
investigate the perinatal period. Being pregnant, delivery and neonatal care
are not separate events, they are part of continuum of professional-care and
self-care that starts with the desire to have a child to bringing the child up,
and supporting the best development possible. We aim for a holistic solution, where
services are accessible and relevant for professionals, parents, the child and
his family in different contexts and time. We investigate and design
product-service systems, and address the complexity, growth and openness of
these systems. Special attention is paid to ensure meaningful experiences in
this domain for the different end-users.
| Category of impact | Research Topic/Theme (at group level) |
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Related content
Research Output
A mathematical model for simulation of early decelerations in the cardiotocogram during labor
Research output: Contribution to journal › Article › Academic › peer-review
Electrohysterography for uterine monitoring during term labour compared to external tocodynamometry and intra-uterine pressure catheter
Research output: Contribution to journal › Article › Academic › peer-review
Orientation of the electrical heart axis in mid-term pregnancy.
Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
Reliability of spectral analysis of fetal heart rate variability
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Wat doet een medisch ingenieur in het ziekenhuis?
Research output: Contribution to journal › Article › Popular
Automated detection of premature atrial contractions in non-invasive fetal heart rate recordings : a case report
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic
Suboptimal bonding impairs hormonal, epigenetic and neuronal development in preterm infants, but these impairments can be reversed
Research output: Contribution to journal › Article › Academic › peer-review
Predictive monitoring of critical cardiorespiratory alarms in neonates under intensive care
Research output: Contribution to journal › Article › Academic › peer-review
Regulatory effects of autonomic nervous system in response to kangaroo care and maturation
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
A strategy to reduce critical cardiorespiratory alarms due to intermittent enteral feeding of reterm neonates in intensive care
Research output: Contribution to journal › Article › Academic › peer-review
Unlike Kangaroo care, mechanically simulated Kangaroo care does not change heart rate variability in preterm neonates
Research output: Contribution to journal › Article › Academic › peer-review
An empirical model for educational simulation of cervical dilation in first-stage labor
Research output: Contribution to journal › Article › Academic › peer-review
Unobtrusive assessment of neonatal sleep state based on heart rate variability retrieved from electrocardiography used for regular patient monitoring
Research output: Contribution to journal › Article › Academic › peer-review
Automatic atlas-based segmentation of brain white matter in neonates at risk for neurodevelopmental disorders
Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
QRS classification and spatial combination for robust heart rate detection in low-quality fetal ECG recordings
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Uterine monitoring techniques from patients' and users' perspectives
Research output: Contribution to journal › Article › Academic › peer-review
The development of an obstetric tele-monitoring system
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Does the architectural layout of a NICU affect alarm pressure? A comparative clinical audit of a single-family room and an open bay area NICU using a retrospective study design
Research output: Contribution to journal › Article › Academic › peer-review
Connected baby bottle: a design case study towards a framework for data-enabled design
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Normal ranges for fetal electrocardiogram values for the healthy fetus of 18-24 weeks of gestation: a prospective cohort study
Research output: Contribution to journal › Article › Academic › peer-review
Selective heart rate variability analysis to account for uterine activity during labor and improve classification of fetal distress
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Interventions for intrauterine resuscitation in suspected fetal distress during term labor: A systematic review
Research output: Contribution to journal › Article › Academic › peer-review
Composite state machine miner: discovering and exploring multi-perspective processes
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Prematurity and the physiology of bonding: a scientific perspective on love
Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Simulation of fetal heart rate variability with a mathematical model
Research output: Contribution to journal › Article › Academic › peer-review
Relative versus absolute rises in T/QRS ratio by ST analysis of fetal electrocardiograms in labour: A case-control pilot study
Research output: Contribution to journal › Article › Academic › peer-review
Deep learning approach for ECG-based automatic sleep state classification in preterm infants
Research output: Contribution to journal › Article › Academic › peer-review
Insight into variable fetal heart rate decelerations from a mathematical model
Research output: Contribution to journal › Article › Academic › peer-review
Effect of tocolytic drugs on fetal heart rate variability: a systematic review
Research output: Contribution to journal › Article › Academic › peer-review
Discovering and Exploring State-based Models for Multi-perspective Processes
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
A study of short cessations and temporal dynamics of breathing in preterm infants
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
How to improve ST-analysis in fetal monitoring: Relative versus absolute t/qrs ratio rises
Research output: Contribution to journal › Article › Academic › peer-review
Features of heart rate variability capture regulatory changes during kangaroo care in preterm infants
Research output: Contribution to journal › Article › Academic › peer-review
A systematic review of prenatal screening for congenital heart disease by fetal electrocardiography
Research output: Contribution to journal › Article › Academic › peer-review
Viewpoints of parents and nurses on how to design products to enhance parent–infant bonding at neonatal intensive care units: a qualitative study based on existing designs
Research output: Contribution to journal › Article › Academic › peer-review
Enabling Process Mining on Sensor Data from Smart Products
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Improved ultrasound transducer positioning by fetal heart location estimation during Doppler based heart rate measurements
Research output: Contribution to journal › Article › Academic › peer-review
Assessment tool for the instructional design of simulation-based team training courses: the ID-SIM
Research output: Contribution to journal › Article › Academic › peer-review
Cardiorespiratory coupling in preterm infants
Research output: Contribution to journal › Article › Academic › peer-review
An innovative design for cardiopulmonary resuscitation manikins based on a human-like thorax and embedded flow sensors
Research output: Contribution to journal › Article › Academic › peer-review
Estimating the error in spectral analysis of fetal heart rate variability
Research output: Contribution to conference › Abstract › Academic
The use of a stronger instructional design by implementing repetitive practice in simulation-based obstetric team training: trainees' satisfaction
Research output: Contribution to journal › Article › Academic › peer-review
KPI-based activity planning for people working in flexible processes
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Fetal heart rate variability analysis for detection of asphyxia can be improved by including uterine activity information
Research output: Contribution to conference › Abstract › Academic
A fixed-lag Kalman smoother to filter power line interference in electrocardiogram recordings
Research output: Contribution to journal › Article › Academic › peer-review
Simulating the effect of uterine contractions on uterine blood flow and fetal oxygenation
Research output: Contribution to conference › Poster › Academic
Construction requirements for full-term newborn simulation manikin
Research output: Contribution to conference › Abstract › Academic
Full-term Infant Simulation Model
Research output: Contribution to conference › Poster › Academic
Detection rate of fetal distress using contraction-dependent fetal heart rate variability analysis
Research output: Contribution to journal › Article › Academic › peer-review
Automated preterm infant sleep staging using capacitive electrocardiography
Research output: Contribution to journal › Article › Academic › peer-review
Dose evaluation for digital X-ray imaging of premature neonates
Research output: Contribution to journal › Article › Academic › peer-review
A simulation model to study maternal hyperoxygenation during labor
Research output: Contribution to journal › Article › Academic › peer-review
A mathematical model to simulate the cardiotocogram during labor. Part A: model setup and simulation of late decelerations
Research output: Contribution to journal › Article › Academic › peer-review
A ballistographic approach for continuous and non-obtrusive monitoring of movement in neonates
Research output: Contribution to journal › Article › Academic › peer-review
Safe patient monitoring is challenging but still feasible in a neonatal intensive care unit with single family rooms
Research output: Contribution to journal › Article › Academic › peer-review
Guided interaction exploration in artifact-centric process models
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Ultrasound transducer positioning feedback for fetal heart rate monitoring
Research output: Contribution to conference › Poster › Academic
Comparison of the psychological and physiological effects on students of a video-assisted or text introduction to a simulated task
Research output: Contribution to journal › Article › Academic › peer-review
Using uterine activity to improve fetal heart rate variability analysis for detection of asphyxia during labor
Research output: Contribution to journal › Article › Academic › peer-review
Could electrohysterography be the solution for external uterine monitoring in obese women?
Research output: Contribution to journal › Article › Academic › peer-review
Respiration monitoring for premature neonates in NICU
Research output: Contribution to journal › Article › Academic › peer-review
Relevance of waveform information displayed on nurses' handheld devices in a single-family room neonatal intensive care unit
Research output: Contribution to journal › Meeting Abstract › Academic
The heuristics of nurse responsiveness to critical patient monitor and ventilator alarms in a private room neonatal intensive care unit
Research output: Contribution to journal › Article › Academic › peer-review
Oxytocin in saliva as a biological marker during Kangaroo care, a feasibility study
Research output: Contribution to conference › Abstract › Academic
Practice variation in the management of intrapartum fetal distress in The Netherlands and the Western world
Research output: Contribution to journal › Article › Academic › peer-review
Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: Study protocol for a randomised controlled trial (INTEREST O2)
Research output: Contribution to journal › Article › Academic › peer-review
Simulation of reflex late decelerations in labor with a mathematical model
Research output: Contribution to journal › Article › Academic › peer-review
Antenatal mother–infant bonding scores are related to maternal reports of infant crying behaviour
Research output: Contribution to journal › Article › Academic › peer-review
Video-based discomfort detection for infants
Research output: Contribution to journal › Article › Academic › peer-review
Simulating fetal heart rate variations : towards clinical application through model reduction
Research output: Contribution to conference › Poster › Academic
Maternal hemoglobin level and its relation to fetal distress, mode of delivery, and short-term neonatal outcome: a retrospective cohort study
Research output: Contribution to journal › Article › Academic › peer-review
Alarm management in a single-patient room intensive care units
Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Automated discomfort detection for premature infants in NICU using time-frequency feature-images and CNNs
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Pattern discovery in critical alarms originating from neonates under intensive care
Research output: Contribution to journal › Article › Academic › peer-review
A showcase of data-enabled design explorations
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Changes in autonomic regulation due to Kangaroo care remain unaffected by using a swaddling device
Research output: Contribution to journal › Article › Academic › peer-review
Prediction of pre-eclampsia by maternal characteristics : A case-controlled validation study of a Bayesian network model for risk identification of pre-eclampsia
Research output: Contribution to journal › Article › Academic › peer-review
Correction to: Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: study protocol for a randomised controlled trial (INTEREST O2)
Research output: Contribution to journal › Article › Academic › peer-review
Unobtrusive sleep state measurements in preterm infants - A review
Research output: Contribution to journal › Article › Academic › peer-review
Hugsy: a comforting solution for preterm neonates designed to enhance parent-child bonding
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Clinical use of electrohysterography during term \labor: a systematic review on diagnostic value, advantages, and limitations
Research output: Contribution to journal › Article › Academic › peer-review