This course aims to provide a deep insight in how nanostructured materials can be modelled within the framework of quantum chemistry by means of electronic structure calculations. The fundamental theory behind electronic structure calculations will be explained to teach the student the approximations and limitations that underly the method. To bring theory to practice, it will be demonstrated how electronic structure calculations can be applied to effectively model the bonding properties of nanostructured materials such as molecules, organometallic complexes, (supramolecular) polymers, pure metals and catalysts. This course is suitable for students of both the MSMC and CPT tracks as well as students from applied physics and biomedical engineering.