Quality and reliability engineering is becoming increasingly important because of the intense global competition and higher customer expectations. Manufacturers have to develop products with enhanced levels of quality and reliability in shorter product-cycle times at reduced costs. Throughout all phases of a product lifetime, the reliability and quality of products must be assured: producersneed to be able to estimate quantitatively the quality and reliability of their products and production processes to know how to improve both when required. Reliability and maintainability engineering is also fundamental to support planning of cost-effective maintenance of systems and the corresponding service logistics. Asset-intensive industries are nowadays paying increasing attention towards smart maintenance of systems. The concepts and methods from reliability and maintainability engineering constitute the necessary foundations for smart maintenance in industry 4.0This course focuses on quantitative methods in reliability and maintainability engineering, statistical process control and quality control, to cope with the above challenges.