Pharmacology

URL study guide

https://tue.osiris-student.nl/onderwijscatalogus/extern/cursus?cursuscode=8RC00&collegejaar=2025&taal=en

Description

This subject deal with the field of drug discovery in a broad perspective. Typical elements of the drug discovery process will be discusses, but also the biological targets of drugs, the effect of a drug on the body (pharmacodynamics) and the effect of the body on the drug (pharmacokinetics) will be discussed.
The course starts with an overview of the drug discovery process. The history, current status and challenges will be discussed here. After this the following topics will be dealt with:

• Drug targets
• Pharmacodynamics
• Pharmacokinetics
• Medicinal Chemistry
• Proteases
• Nuclear Receptors
• Kinases

De diverse topcis will be illustrated with examples of applications of medicines. The students will go in depth using self-study and presentation topics and the course will be finalized with an exam.

Objectives

After passing the course, the student has:

1. Insight in the process of drugs discovery and can describe medicine and their development.
2. Knowledge of basic principles of farmacokinetics and –dynamics and can use this when analyzing pharmacological results and their description.
3. Developed chemical knowledge through medicinal chemistry and can use this when analyzing and describing metabolic processes and molecular drug-target interactions.
4. Knowledge of important drug targets (proteins) and their relation to diseases and can describe these concepts and the relation between them.
5. Knowledge and insight in the basics of pharmacological systems (cardiovascular system, blood coagulation, central nervous system) when describing them.

Method of Assessment

Written examination