This course deals with the design, planning and control of complex industrial systems. , Ffor example, a digital and sustainable factory, taking into account the technological, economical and organizational constraints that a design must satisfy. The students are expected to apply the fundamental steps of a design cycle, with a particular focus on the development and performance evaluation of a conceptual design followed by a subsequent detailed design. The course will follow the principles of challenge-based learning, with cases motivated by the real-life problems in companies from the high-tech industry of the Brainport region.