URL study guide
https://tue.osiris-student.nl/onderwijscatalogus/extern/cursus?cursuscode=6BMR04&collegejaar=2025&taal=enDescription
This course covers an introduction to biochemistry and biotechnology, with in specific, the relation between organic chemistry andbiochemistry, the composition and build-up of peptides and proteins, knowledge of amino acids, secondary structure and 3D folding,
the working mechanisms of important enzyme classes, including kinetics, protein purification methods, structure of nucleic acids, DNA replication
and DNA recombinant technology, transcription of DNA into RNA, translation of RNA into proteins, and the design of reactor processes.
Extra information about the assessment
The grades for the practical component (lab report 1 and 2) are valid for 6 academic years. The results of the final exam are only valid in the academic year in which they were taken.
The final course grade will be the weighted average, which should by at least a 5.5 to pass the course.
In case of an insufficient grade for the lab report (lab report 1 and/or lab report 2), there is a resit opportunity for the lab report after quartile 4. The deadline for the revised lab report will be determined by the responsible lecturer, and will be no longer than 3 months after the quartile ended, and will be before the end of the respective academic year. The maximum grade for the resit of the lab report will be a 5.5; in case the obtained result will be higher than a 5.5, the result will be adjusted to a 5.5.
Extra information about register
To register for this course via Osiris, you must have completed the safety test of 6BBR02 with at least a 6.0. If you are unable to register for this course, but do meet the admission requirements, please contact the Center of Student Administrations of Chemical Engineering & Chemistry (CSA-CEC) via email: [email protected]
Extra General info:
A student may only be absent for at most 5% of the scheduled hours of the practical component of this course
, with an, according to the opinion of the board examiners, legitimate reason. Only if the absence of student hinders the continuation of the project, a student needs to catch up for the missed hours A student informs the lecturer about his or her absence right away If a student is absent for more than 5% of the scheduled time, in any case, possibilities to catch up for the missed hours need to be discussed with the lecturer of the course. The lecturer can oblige a student to re-sit part or the whole course later.
Objectives
- The student is able to describe the structure of biomolecules and explain how this relates to function.
- The student is able to solve standard kinetic questions related to enzyme activity.
- The student is able to use kinetic data to design reactor processes.
- The student is able to describe the information flow within a cell: from DNA to protein.
- The student is able to describe the process of cell growth.
- The student is able to apply recombinant DNA technology experimentally.
- The student is able to perform basic biochemistry experiments.
- The student is able to perform an enzymatic conversion in flow.
- The student is able to assess and compare the performance of a Batch reactor, CSTR and PFR.
- The student is able to describe how the reactor temperature, volume, and throughflow determine the performance.
- The student is able to write a lab report.