Basic tissue engineering

Course

URL study guide

The course is centered on roughly five themes that concentrate on:

Introduction to tissue engineering: Definitions, historical/worldwide perspective, general introduction to tissue engineering
Cellular aspects: Overview over cells typically used for tissue engineering application: cell types, cell sources, stem cells
Biomaterial scaffolds: Bulk material vs scaffolds, limitations of existing biomaterials solutions, highlighting the important medical needs, choice of material, structure, processing methods
Construct Technology: 2D vs 3D culturing techniques, proliferation and differentiation, scaffold-free cell culturing techniques, seeding cells onto 3D scaffolds, mechanobiology in tissue engineering
Tissue development: Tissue development is a dynamic process, the use of computational models in TE, bioreactors for TE applications, longitudinal monitoring, feedback-loops/automation
Increased complexity: 3D (bio) printing
Upscaling: Preservation of tissue engineered constructs, vascularization, co-cultures, , organs-on-a-chip, personalized medicine

After passing the course, the student:

... has insight in the multidisciplinary principles underpinning tissue engineering and can outline the conceptual strategies from various viewpoints.
... has insight into the scientific principles that underlie a series of repair strategies and can describe and apply these principles to specific tissues.
... can integrate the knowledge on tissue engineering by describing and reflecting on challenges associated with the tissue engineering industry and the translation to the clinics.
... can reflect on results typically obtained by tissue engineering experimental setups.

Digi STEP Ans