Systems Biology of Disease Progression

    Press/Media: Research

    Description

    ADAPT (Analysis of Dynamic Adaptations in Parameter Trajectories) is a modeling approach to simulate the progression of metabolic diseases. The method, originally developed at the Eindhoven University of Technology, can also be applied to evaluate the long-term effects of pharmacological interventions. Using a Systems Biology approach, experimental data from longitudinal studies are integrated in mechanism-based disease progression models. ADAPT identifies the biological processes that are disturbed and collectively induce the disease. Such information can be used for the development of therapies, improved diagnosis and prevention.

    Period12 Feb 2014

    Media contributions

    1

    Media contributions

    • TitleSystems Biology of Disease Progression
      Degree of recognitionInternational
      Media name/outletYouTube
      Media typeWeb
      Duration/Length/Size2:16
      Country/TerritoryNetherlands
      Date12/02/14
      DescriptionADAPT (Analysis of Dynamic Adaptations in Parameter Trajectories) is a modeling approach to simulate the progression of metabolic diseases. The method, originally developed at the Eindhoven University of Technology, can also be applied to evaluate the long-term effects of pharmacological interventions. Using a Systems Biology approach, experimental data from longitudinal studies are integrated in mechanism-based disease progression models. ADAPT identifies the biological processes that are disturbed and collectively induce the disease. Such information can be used for the development of therapies, improved diagnosis and prevention.
      Producer/Author ICMS Animation Studio
      URLhttps://www.youtube.com/watch?v=x54ysJDS7i8
      PersonsNatal A.W. van Riel
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